Treatment with Isotretinoin (for acne and acne-like skin conditions)

Isotretinoin is a proven, effective, and safe oral treatment used for a variety of skin conditions, including acne, folliculitis, and rosacea. The treatment works by reducing sebum production and also has an anti-inflammatory effect on the skin.

Skin conditions can cause symptoms such as blemishes, redness, and swelling, which can affect both appearance and quality of life. The goal of treatment with isotretinoin is to reduce or eliminate these symptoms and achieve a cosmetically acceptable result.

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What symptoms can isotretinoin treatment help with?

Treatment with isotretinoin at our dermatology clinic is recommended for acne and acne-like skin conditions that cause blemishes, redness, and swelling—and that often affect both appearance and quality of life. Below are some of the most common symptoms that lead patients to schedule an appointment at Capio.

If you're unsure whether your symptoms fit the description, you're always welcome to contact us.

Pimples and inflamed breakouts on the face

Red, tender bumps and pus-filled pimples on the cheeks, forehead, chin, or jawline. The dermatologist will assess the type and severity of your acne and determine whether oral treatment with isotretinoin is the right solution for you.

Blackheads, clogged pores, and oily skin

Blackheads, whiteheads, visible pores, and skin that constantly feels oily. Isotretinoin works by reducing sebum production and reducing inflammation in the skin.

Deep lumps and cysts under the skin

Large, tender lumps and cysts that sit deep within the skin and tend to leave scars. This type of acne usually requires internal treatment and should be evaluated by a dermatologist.

Acne on the back, chest, and shoulders

Acne isn't always limited to the face. Breakouts on the back, chest, shoulders, and upper arms can be difficult to treat with creams alone because these areas are large and the skin is thicker.

Acne that hasn't cleared up with cream or antibiotics

Have you tried skincare products, prescription creams, or antibiotic treatments without lasting results? Isotretinoin is a proven oral treatment that helps 80–85% of patients achieve completely or nearly completely clear skin.

Acne Scars and Discoloration

Red or dark spots and early signs of scarring from previous breakouts. The sooner active acne is brought under control, the lower the risk of permanent scarring—which is why it’s a good idea to get evaluated in a timely manner.

Rosacea with redness and bumps

Persistent redness in the center of the face, visible blood vessels, and acne-like bumps and swelling. Rosacea is one of the skin conditions for which isotretinoin can be used when other treatments are not effective enough.

Folliculitis and Inflamed Hair Follicles

Recurrent inflamed hair follicles with small, tender bumps—for example, on the face, neck, chest, or back. A dermatologist will determine the cause and assess whether you might benefit from treatment with isotretinoin.

Impact and expected results

Isotretinoin is a well-established treatment that has been in use since the 1980s and is highly effective for conditions such as acne, folliculitis, and rosacea.

At the start of treatment, symptoms may temporarily worsen, but this will quickly subside. After that, most people will begin to notice an improvement within the first month and a significant improvement after 2–3 months.

The results vary from person to person depending on the type and severity of the skin condition, but 80–85% of patients achieve a completely or nearly completely acne-free outcome. The goal of treatment is to reduce or eliminate the discomfort caused by the skin condition and improve quality of life.

Course of treatment

Treatment with isotretinoin is planned in collaboration with a dermatologist following an initial evaluation. The course of treatment typically lasts approximately 6 consecutive months, depending on the type and severity of the skin condition. If the dermatologist determines that treatment should continue beyond six months, the necessary blood tests, prescription renewals, and consultations are included at no additional charge for up to 12 consecutive months from the start of treatment.

During treatment, regular blood tests are required to monitor kidney, liver, and cholesterol levels, among other things. Regular check-ups are also scheduled, which can take place either in person or via video consultation.

Blood tests are taken before treatment begins and after approximately one month of treatment. After that, women who can become pregnant generally have monthly blood tests, while men and women who cannot become pregnant generally have blood tests every three months. You will receive an individualized plan during the initial evaluation. Once the blood tests have been evaluated, a prescription will be issued, and you must pick up the medication at the pharmacy within 7 days.

Precautions during treatment

There are a number of precautions that must be followed during treatment with isotretinoin. Women must not be pregnant or become pregnant during treatment and must use effective contraception. The treatment must also not be used while breastfeeding or in cases of known liver disease.

You are not permitted to donate blood during treatment or for the first month after treatment ends. When spending time in the sun, it is recommended that you use sunscreen with a high SPF (SPF 50+) and avoid intense sun exposure.

Moderate alcohol consumption generally poses no significant risks, but heavier drinking can affect liver function tests; therefore, it is recommended that you follow the guidelines issued by the Danish Health Authority.

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Frequently Asked Questions About Isotretinoin Treatment

Who is eligible for treatment with isotretinoin?

Isotretinoin may be appropriate for acne, rosacea, or recurrent inflammation of the hair follicles. The treatment is used, among other things, for severe or persistent acne that has not improved sufficiently with prescription creams or antibiotics. During an initial consultation, the dermatologist will evaluate your skin condition and determine whether isotretinoin is the right treatment for you.

How does isotretinoin work to treat acne?

Isotretinoin is a vitamin A-like medication that reduces the skin’s production of sebum and suppresses inflammatory processes. The treatment can therefore reduce blackheads, pimples, redness, and swelling. The effect varies from person to person, but according to Capio’s patient information, 80–85% of patients achieve a completely or nearly completely acne-free result.

How quickly does isotretinoin work, and how long does the treatment last?

At first, symptoms may temporarily worsen. Most people begin to see an improvement within the first month and a significant improvement after 2–3 months. A course of treatment typically lasts about six months, but the duration depends, among other things, on the type and severity of the skin condition, as well as individual factors.

What side effects can isotretinoin cause?

The most common symptoms are dry skin and dry lips. The mucous membranes in the eyes and nose may also become dry, and some people experience muscle and joint soreness. A dermatologist can provide advice on skin care and other measures that may alleviate these symptoms. Unexpected changes in mood or mental state should be taken seriously and discussed with your doctor.

Why do I need to have blood tests during treatment?

Blood tests are used, among other things, to monitor liver and kidney function, cholesterol levels, and the fat content in the blood. Blood tests are taken before treatment begins and again after about one month. After that, women of childbearing age generally have blood tests every month, while other patients typically have blood tests every three months. You will receive a personalized plan during the initial evaluation.

Can I take isotretinoin if I am pregnant or breastfeeding?

No. Isotretinoin must not be used during pregnancy or while breastfeeding. Women who could become pregnant must use reliable contraception during treatment and follow the dermatologist’s plan for pregnancy tests. The treatment also cannot be administered if you have a known liver disease. The dermatologist will review the relevant precautions with you before treatment begins.